منابع مشابه
Overdiagnosis in cancer.
This article summarizes the phenomenon of cancer overdiagnosis-the diagnosis of a "cancer" that would otherwise not go on to cause symptoms or death. We describe the two prerequisites for cancer overdiagnosis to occur: the existence of a silent disease reservoir and activities leading to its detection (particularly cancer screening). We estimated the magnitude of overdiagnosis from randomized t...
متن کاملConceptualizing overdiagnosis in cancer screening.
The aim of cancer screening is to detect asymptomatic cancers whose treatment will result in extension of life, relative to length of life absent screening. Unfortunately, cancer screening also results in overdiagnosis, the detection of cancers that, in the absence of screening, would not present symptomatically during one's lifetime. Thus, their detection and subsequent treatment is unnecessar...
متن کاملRevisiting overdiagnosis and fatality in thyroid cancer.
OBJECTIVES To examine the rates of incidence and fatality in cohorts of patients diagnosed with thyroid cancer from 1975 to 1999. METHODS This study uses National Cancer Institute's Surveillance, Epidemiology and End Results data and derives hazard functions in order to examine the fatality in thyroid cancer. RESULTS The study documents forms of rapidly evolving and fatal tumors as well as ...
متن کاملDowngrading cancer definitions: overdiagnosis fuels the discussion.
Effects of Social Support and Isolation Lutgendorf is also examining links between depression and social support or isolation and survival in ovarian cancer patients. She studied the presence of MMPs, vascular endothelial growth factor, interleukin 6, tumor norepinephrine, and NK cells. She found associations between these protumor substances and social isolation. Patients with higher levels of...
متن کاملOn the Social Construction of Overdiagnosis; Comment on “Medicalisation and Overdiagnosis: What Society Does to Medicine”
In an interesting article Wieteke van Dijk and colleagues argue that societal developments and values influence the practice of medicine, and thus can result in both medicalisation and overdiagnosis. They provide a convincing argument that overdiagnosis emerges in a social context and that it has socially constructed implications. However, they fail to show that overdiagnosis per se is socially...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 2018
ISSN: 0959-8138,1756-1833
DOI: 10.1136/bmj.k3528